| Funding Opportunities (Projects and Programmes)
1. NIHR Invention for Innovation (i4i) – Challenge Awards (Closing Date: 29 May 2013, 1pm) The NIHR i4i Challenge Awards seeks to identify those medical technologies with the greatest potential clinical benefit, along with how they might be integrated into clinical decision and treatment pathways and be implemented on a large scale. Research proposals are invited from NHS organisations or other providers of NHS services in England, in cooperation with commercial and Higher Education Institution (HEI) partners as appropriate, to develop non-pharmaceutical, implantable technologies for sight or hearing loss. 2. DH Academic Health Science Centres competition (Closing Date: 31 May 2013) The Department of Health has launched a new, open, two-stage competition to designate Academic Health Science Centres (AHSCs) in England. The role of the newly designated AHSCs will be to increase strategic alignment of NHS providers and their university partner, specifically in world-class research, health education and patient care, in order to improve health and healthcare delivery, including through increased translation of discoveries from basic science into benefits for patients. AHSCs will be able to realise their potential as drivers of economic growth through research partnerships with commercial life science organisations. Designation will be for five years from 1 April 2014. The closing date for submission of the Pre-qualifying Questionnaire by NHS provider/ university partnerships in England that are interested in being considered for AHSC designation is 31 May 2013 at 1.00pm. The NIHR Central Commissioning Facility (CCF) is managing the call and designation process on behalf of the Department of Health. 3. NIHR/MRC EME Programme – Commissioned work stream (Closing Date: 3 June 2013, 1 pm) The Efficacy and Mechanism Evaluation (EME) Programme invites research proposals to evaluate innovative and novel healthcare treatments and tests delivered through industry-academia-NHS collaborations, which address priority areas of unmet need in the following areas: • Alcohol and substance misuse in younger people (to exclude nicotine) • Radionuclide imaging in non-malignant disease 4. NIHR Health Technology Assessment Programme – Commissioned call for proposals (Closing Date: 29 August 2013, 1pm) The NIHR Health Technology Assessment (HTA) Programme invites research proposals in the following area: Multiparametric MRI in planning epilepsy surgery. 5. NIHR Health Technology Assessment Programme – Primary care research Commissioned calls (Closing Date: 29 August 2013) The NIHR Health Technology Assessment (HTA) Programme invites research proposals on the following areas: • Immunisation of Children and Young People Looked After By the State • Feasibility of psychosocial interventions for preventing blood borne virus infection in people who inject drugs • Peer support for breastfeeding maintenance • A prognostic tool to aid clinical management decisions in acute ankle sprain • Prognostic models for people with advanced cancer • Suspected acute pulmonary embolism in pregnancy • Mechanical Insufflation-Exsufflation devices for assisted cough in neuromuscular disease • Early pulmonary rehabilitation after an exacerbation of Chronic Obstructive Pulmonary Disease (COPD) • Interventions to enhance engagement in exercise referral schemes • Non-neuroleptic mood stabilising medication for challenging behaviour in adults with intellectual disability The deadline for submission of outline proposals is 29 August 2013 by 1pm.
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| Funding Opportunities (Fellowships)
1. Royal College of Radiologists Constance Thornton fellowship (Closing Date: 7 June 2013) The Royal College of Radiologists invites applications for the Constance Thornton fellowship. This supports a research project or furthers a radiological interest in the UK or abroad. Preference will be given to applications centred either on cross-sectional imaging or paediatric radiology, and especially to projects likely to lead to publication. Application is open to members and fellows of the college’s faculty of clinical radiology who hold a clinical radiology post in the UK. The fellowship is worth £3,000. 2. Medical Research Council Population health scientist fellowship (Closing Date: 19 June 2013) The Medical Research Council invites applications for its population health scientist fellowship. This fellowship provides support for research and specific training for pre- and postdoctoral researchers and clinical scientists, including specialist trainees, general practitioners, dentists, nurses, midwives and members of the allied health professions. Disciplines relevant to the scheme include: social, clinical, life course and genetic epidemiology; biostatistics; health demography; medical sociology; health psychology; medical anthropology; human geography; health economics. The research fellowship provides the opportunity to spend time in an overseas research centre, a second UK research centre or UK industrial centre. MRC would normally support with justification one visit, which may be no longer than 12 months. Science graduate applicants should hold a PhD or DPhil in a relevant discipline. Applicants who hold a research-oriented master’s degree will also be considered. Medical or dental graduates should be post-registration up to and including specialty registrar grade. Nurses, midwives and members of the allied health professions must have completed their professional training and hold a master’s degree, or equivalent postgraduate research-oriented qualification. Fellows may be based at UK universities, medical or dental schools, Research Council institutes and units, charity-funded research centres, or other approved academic institutions. The fellowship lasts for up to three years. At the postdoctoral level, the award covers salary, training costs, consumables, travel costs and capital equipment, and all other relevant costs under full economic costs. At the predoctoral level, the fellowship includes salary up to NHS consultant level, and a research training support grant of up to £15,000 per year. 3. Medical Research Council Early career fellowship in economics of health (Closing Date: 19 June 2013) The Medical Research Council invites applications for its early career fellowship in economics of health. The scheme enables individuals to undertake challenging projects in excellent research and training environments in the UK. MRC aims to strengthen capacity in health economics by attracting early postdoctoral researchers trained in economics research methods to apply their skills to health economics problems. The fellowship helps individuals begin to establish a research track record in the field and to undertake further training. The competition is open to applicants with some advanced training in any field of economics who can demonstrate the transferability of their research skills to the field of the economics of health. It is also open to applicants who have recently transferred to health economics and require further advanced training. Those with prior training in econometric methods are particularly encouraged to apply. Applicants must either have a PhD or expect to do so by the time of take-up of the award, and must not have more than four years’ postdoctoral experience. The fellowship is for a period of up to three years. 4. Medical Research Council Methodology research Fellowship (Closing Date: 19 June 2013) The Medical Research Council invites applications for its methodology research fellowship. The scheme is aimed at researchers with a grounding in health research, not necessarily in a methodological discipline, to enable them to move from postdoctoral scientist to an independent researcher in their chosen research field. The scheme is open to applicants who wish to pursue development, validation and application of innovative methodologies in one or more of the following disciplines: •health economics; •biostatistics and bioinformatics; •modelling, decision sciences and epidemiology; •clinical trials; •behavioural sciences; •health psychology; •qualitative methodologies and mixed methods; •medical sociology; •medical geography. Science and social science graduates should hold a PhD or DPhil in a relevant discipline and have between three and six years’ postdoctoral experience. Applicants who hold a relevant research-orientated master’s degree will also be considered. Other relevant disciplines include those that support clinical research directly, as well as nurses, midwives and members of the allied health professions. Medical or dental graduates should be post registration, including specialty registrar. Applications from MRC fellows and postdoctoral researchers returning from overseas are particularly welcome. Fellows may be based at UK universities, medical or dental schools, hospitals, general practices, research council institutes and units, charity-funded research centres, or other approved academic institutions. The fellowship lasts up to four years and provides the fellow’s competitive salary and necessary research and other costs allowable under full economic costs. The fellowship also provides the opportunity to spend time in an overseas research centre, a second UK research centre or UK industrial centre. 5. Medical Research Council Career development award in biostatistics (Closing Date: 19 June 2013) The Medical Research Council invites applications for its career development award in biostatistics. This aims to support outstanding individuals who have recently completed their PhDs and who are working in, or seeking to move into, statistically based health-related research in the UK. It provides up to four years of support for the development and investigation of innovative statistical methods and their application in clinical research. The award also provides the opportunity to spend time in an overseas research centre, a second UK research centre or UK industrial centre in year two or three of the award. The scheme is open to individuals with PhDs in statistics, biostatistics or a related discipline and less than four years of postdoctoral experience. Candidates without medical statistical experience are welcome to apply. Applicants have no residential restrictions and may come from any country. The fellowship covers salary, research training support costs, annual travel or overseas costs, equipment, and all other relevant costs under full economic costs. |
| Funding Opportunities (Studentships)
1. Alzheimer’s Society PhD studentship grants (Closing Date: 31 May 2013) The Alzheimer’s Society invites applications for its PhD studentships. These provide funding for new PhD studentships in the areas of cause, cure, care or prevention of dementia. Applications should be made by the prospective supervisor. Up to £85,000 may be requested to cover a fixed stipend, fees, materials and consumables. 2. Parkinson’s UK PhD studentship (Closing date: 17 June 2013) Parkinson’s UK invites applications for its PhD studentships. These are offered to outstanding students undertaking research into Parkinson’s. Funding is available over three years to students based at UK higher education institutions and provides: •a stipend of £15,000 per year (or £16,000 per year if in London); •full PhD tuition fees at the UK/EU rate; •a contribution of up to £10,000 per year towards research costs. Students from outside the EU are welcome to apply for this scheme on a full fee-paying basis. Home and overseas students must have a first or upper second class honours degree in a relevant subject. Applications must be made by the potential student’s supervisor, who must hold a tenured position at a UK university, hospital or research institute. 3. Arthritis Research UK PhD studentships (Closing date: 7 Aug 2013) Arthritis Research UK invites applications for its PhD studentships. These are awarded to university departments for projects that have clear relevance to the aims of Arthritis Research UK and provide training in research in a multidisciplinary environment. Applications may include a named student or, alternatively, students may be recruited after the studentship is awarded. Proposals may also be submitted for collaborative studentships by universities with an industrial sponsor. Awards consist of a tax-free incremental stipend, worth a maximum of £23,673 per year, UK tuition fees and limited running costs over three years. |
Tag Archives: health
Lincoln funding: LN6 Active Community Grants Scheme
Community groups and organisations can apply now for grants of up to £1,000 for projects which encourage more people in the LN6 postcode area of Lincolnshire to be active, more often.
The LN6 Active Community Grants scheme is provided by Lincolnshire County Council and administered by Lincolnshire Sports Partnership which is a registered charity.
Access LN6 is a £6.5 million programme which aims to improve sustainable transport options in the LN6 area and increase opportunities to walk, cycle and use public transport, as well as improving health throughout the community.
Grants are for the development or support of activities within the LN6 area which encourage people to be active.
There will be two funding rounds with £20,000 available in total. Grants can cover 100% of the project costs up to a maximum level of £1,000.
To be eligible, applicants must:
- Be a registered charity, voluntary group, sports club, parish council or social enterprise.
- Have a constitution or governing document.
- Have a bank account (or evidence that an account is being set up).
- Have a project or activity taking place in the LN6 postcode area.
Grants can only be used for community events and activities that will directly result in more people being more active on a regular basis.
Projects must:
- Take place within the LN6 postcode area.
- Help promote participation in physical activity particularly through volunteering effort.
- Uphold equalities and the principle of fair and open access to all local people.
- Be new and sustainable events or activities.
Examples of the type of costs that can be supported include:
- Revenue and capital costs.
- Training.
- Equipment purchase.
- Volunteer expenses.
- Meeting room and hall hire.
The first application deadline is 17 June 2013 (5pm).
To apply, please visit the Partnership’s website, or contact Research and Income Generation Support at Research and Enterprise.
Source: GRANTfinder Newsflash
Plug in to a healthier future
Research to set up an online system enabling doctors to access patients’ health records from all across the European Union, has been launched.
The European Commission project, MyHealthAvatar, is designed to give people more knowledge and control of their health via their computers and mobile phones.
The programme will keep archives of each user’s electronic health records, as well as store data about daily activities and family history.
These combined factors, which may influence general health, would then be collated to predict and prevent potential
diseases such as various forms of cancer.
It will also build a consistent continent-wide record of individual citizens enabling effective treatment should travellers become unwell anywhere in the EU.
The three year, 2.4 million euro study is dedicated to developing novel approaches to provide a solution that offers access, collection, sharing and intelligent analysis of long-term and consistent personal health status data through an integrated digital representation in silico environment.
This will help to deliver clinical analysis, prediction, prevention and treatment tailored to the individual subject.
The UK’s University of Bedfordshire’s Professor of Visual Computing, Feng Dong, is leading the scheme which is being worked on with a consortium of universities and hospitals around Europe, including the University of Lincoln (UK).
Professor Dong, who will be working with a team from the University’s Centre for Computer Graphics and Visualisation, believes the avatar “could reshape the future of healthcare”.
He said: “Although there have been similar projects to this in the past, we are hoping to learn from previous ideas which didn’t quite work to make MyHealthAvatar successful. I think one of the key issues is to make it people friendly and for it to be easy-to-use. Most of the data for the Avatar will come from the system itself and there is very little for the user to actually insert, or do.
“With today’s technology it is possible to use a person’s information from sites such as Twitter and Facebook to give us more details about a patient. With mobile phone tagging it is also possible for the system to show where the patient has been. So for example if they are regularly in the pub, it could suggest to the user that they are drinking too much.
“Additionally if they go to the doctors and told they have a disease, precise medical information will be sent their way; which a) reduces the need revisit the doctor, and b) helps them research online for healthcare information. So we are hoping this will make MyHealthAvatar stand-out. It’s very exciting to be leading the project and a quite a coup for the University too.”
The University of Lincoln’s Dr Xujiong Ye, who will be working with a team from the University’s Laboratory of Vision Engineering (LoVE), will primarily focus on the area of multi-scale medical image analysis.
Dr Ye, a Reader in the School of Computer Science, said: “We will develop novel image analysis algorithms and approaches using advanced computing technology to support accurate examination and reliable detection of a range of cancer diseases through the information available, from imaging data to histology data. It is expected that the availability of such information will help solve many uncertain cases caused by the ambiguity of data that is often seen at a single scale. For example, the analysis of histology images will provide significant measures to reach more trustworthy decisions for the detection of abnormal structures from the images at the organ level
“We aim to build an infrastructure framework to allow us to collect all the health information required so we can create a 4D digital representation of the patient. This project is expected to exert a major influence on the reshaping of future healthcare in the handling of increased life expectancy and the ageing population.”
Story credits:
Marie Daniels - PR Officer
E-mail: mdaniels@lincoln.ac.uk
Telephone: 01522 886244
Latest Health Research Funding Opportunities
Funding Opportunities (Projects and Programmes)
NIHR HTA Programme – Researcher-led Proposals Closing Date: 07/01/2013
Our researcher-led calls are open all year round, with three application cut-off dates. The next closing date for applications is 1pm on Monday 7 January 2013. Application forms and all associated documents for this call are available on the HTA Programme website.
**For this call, we are particularly interested in receiving proposals assessing very rare diseases. This drive for research proposals is part of an NIHR-wide call to increase research in this area. The specification document is available on the HTA website.**
Proposals deemed within remit for the current call will be assessed for their importance to the NHS in March 2013 and May 2013. Applicants will be advised as to whether they have been short-listed by the end of August 2013.
NIHR Health Services and Delivery Research Programme – Commissioned Closing Date: 17/01/2013
The Health Services and Delivery Research (HS&DR) Programme invites research proposals to improve the quality, effectiveness and accessibility of the NHS in the following areas:
- Evaluating new models of care for people with long-term conditions.
NIHR Research for Patient Benefit (RfPB) programme – competition 20 Closing Date: 23/01/2013
The NIHR RfPB Programme invites applications for applied research projects to provide benefit for NHS patients and other users of health and social care services, including for this call, Applied Clinical Research on Very Rare Diseases. RfPB is a nationally co-ordinated funding stream for regionally commissioned research, which supports research into day-to-day practice of health service staff that can achieve improvements in patient care. Projects are funded to a maximum of £350k for up to 36 months.
Heath Technology Assessment Programme – Management of sciatica Closing Date: 01/02/2013
The NIHR Heath Technology Assessment (HTA) Programme invites research proposals that provide information about the effectiveness, costs and broader impact of healthcare treatments and tests. Outline research proposals are sought on the following topic:
- Management of sciatica (lumbosacral radiculopathy) and suspected sciatica.
Funding Opportunities (Fellowships)
Medical Research Council New investigator research grants – infections and immunity Closing date: 08 January 2013
The Medical Research Council invites applications for its new investigator research grants in infections and immunity. Applicants must be based at a UK institution and hold a PhD, DPhil or an MD. They should either be at the start of their first lecturer appointment and have a minimum of three years post qualification research experience or be in a senior postdoctoral position and have between three and 10 years post qualification research experience. Awards are worth up to £600,000, usually for a period of three years, but applications for a longer period of time are accepted. MRC will usually meet up to 80 per cent of the full economic cost.
Medical Research Council and other Funders Jointly funded clinical research training fellowships Closing date: 15 January 2013
The Medical Research Council invites applications for its jointly funded clinical research training fellowships. In addition to standard clinical research training fellowships, opportunities for jointly funded fellowships are provided through collaborations with RoyalColleges and charities. In the next funding round, joint funding will potentially be available with:
- Alzheimer’s Society: up to two fellowships may be funded each year; Asthma UK; British Association of Dermatologists/British Skin Foundation; British Infection Association; British Lung Foundation/Mick Knighton Mesothelioma Fund; Chronic Granulomatous Disorder Society; Cystic Fibrosis Trust; Fight for Sight; Kidney Research UK: two fellowships will be awarded each year; MND Association Lady Edith Wolfson fellowships;
- Multiple Sclerosis Society; Novo Nordisk UK Research Foundation; Pancreatic Cancer UK; The Prostate Cancer UK; Royal College of Obstetricians and Gynaecologists; Royal College of Ophthalmologists/Novartis; Royal College of Physicians/Dinwoodie Trust; Royal College of Radiologists; Royal College of Surgeons (Edinburgh);
- Sparks: up to two fellowships will be awarded; Stroke Association: up to two fellowships will be awarded;
- Target Ovarian Cancer; Ulverscroft Vision Research Group; Welsh Assembly: two fellowships will be awarded each year.
Any jointly funded fellowships will be offered under standard MRC terms and conditions and at the same funding level as standard clinical research training fellowships. Additional eligibility criteria relating to college membership, clinical training, experience and qualifications may apply: potential applicants should visit the website of the organisation providing funding.
European Society for Paediatric Endocrinology Research Fellowships Closing date: 01 March 2013
The European Society for Paediatric Endocrinology invites nominations for its research fellowships. These enable young paediatricians or scientists to undertake research training for up to two years in a centre of excellence outside their current institution. Short-term fellowships last for two to six months, while long-term research fellowships last for two years. Long-term research fellowships are worth up to €53,600 annually, while short term fellowships are worth up to €13,400 in total. At least six months or up to the full long-term fellowship must be spent in an institution in a foreign country. Each applicant should be fully trained in paediatrics, have received clinical endocrine training at their present institution and be in need of additional specialised research training. Researchers who completed a PhD not longer than four years ago may also apply for long-term research grants. Each applicant should be proposed by their current supervisor or head of department, who must be an ESPE member. All grants are reserved for European researchers.
Medical Research Council Clinician scientist fellowship Closing date: 9 April 2013
The Medical Research Council invites applications for its clinician scientist fellowships. The scheme aims to develop outstanding medically and other clinically qualified professionals to establish themselves as independent researchers. Applicants must demonstrate a rigourous and insightful approach to research, and the ability to relate their research to clinical medicine and to the improvement of health. The following fellowships are available:
- the MRC clinician scientist fellowship is a postdoctoral clinical fellowship providing up to four years’ support. There is also a patient-oriented version of the scheme that provides up to five years’ support and is intended for research which requires up to 40 per cent of the fellow’s time to be spent in clinical work. At least 50 per cent of this clinical work should be of direct relevance to the research project;
- the MRC/Academy of Medical Sciences tenure-track clinician scientist fellowship is designed to support career development and promote recruitment into clinical academic medicine. This award provides up to five years’ support;
- MRC/MND Association Lady Edith Wolfson fellowships enable clinicians to pursue research into the pathogenesis and treatment of motor neurone disease.
Each of the above awards provide the opportunity to spend time in an overseas research centre, UK industry, or a second research centre, for a period of up to one year to receive training that cannot be achieved as effectively within the academic host institution.
The clinician scientist and patient-oriented clinician scientist fellowships are open to hospital doctors, dentists, general practitioners, nurses, midwives and members of the allied health professions. The MRC/Academy of Medical Sciences tenure-track clinician scientist fellowship is open only to hospital doctors, dentists and general practitioners. Medical or dental graduates should be of speciality registrar or consultant status. Nurses, midwives and other allied health professionals must have completed their professional training. All applicants must have obtained a PhD, DPhil or MD in a basic science or clinical research project. All nationalities are eligible to apply.
Fellowships cover salary, support staff, consumables, travel and capital equipment under full economic costs.
Medical Research Council Senior clinical fellowship Closing date: 9 April 2013
The Medical Research Council invites applications for its senior clinical fellowship. This aims to develop outstanding medically and other clinically qualified professionals to become research leaders. There are two types of fellowship:
- the MRC senior clinical fellowship, which provides the salary of the senior clinical fellow who will be an employee of the host institution.
- MRC/MND Association Lady Edith Wolfson fellowship which enables clinicians to pursue research into the pathogenesis and treatment of motor neurone disease.
Each of the awards provide the opportunity to spend time in an overseas research centre, UK industry, or a second research centre, for a period of up to one year to receive training that cannot be achieved as effectively within the academic host institution.
Clinical applicants should hold a PhD/DPhil or MD and will have at least three years’ relevant postdoctoral research experience. The scheme is open to hospital doctors, dentists, general practitioners, nurses, midwives and members of the allied health professions. There are no residence eligibility restrictions.
Funding may cover research support staff, research consumables expenses and capital equipment appropriate for the research project, an annual travel allowance, and other appropriate items under full economic cost. Support is provided for five years.
Funding Opportunities (Studentships)
Heart Research UK Novel and emerging technologies grant Closing date: 01 April 2013
Heart Research UK invites applications for its novel and emerging technologies grant. In addition to research costs, the grant may include support for attending a conference, dissemination of research findings, and a PhD studentship consisting of a stipend of up to £16,000 per year and research costs up to £5,000 per year. The maximum funding amount available is £200,000.
Motor Neurone Disease Association PhD studentship Closing date: 03 May 2013
The Motor Neurone Disease Association invites applications for its PhD studentships. This scheme aims to attract promising science graduates to develop a career in motor neurone disease-related biomedical research. Applications should be submitted by prospective supervisors based in UK laboratories. The association welcomes collaborative projects between departments. Supervisors should recruit and nominate the student of their choice, who should hold, or expect to obtain, a first or upper second class honours degree. Awards will be offered for three years and will consist of:
- a student stipend of £16,000 for the first year (£17,000 in London), which will be increased in £500 increments for each of the following two years;
- £8,000 per annum for laboratory expenses;
- a total budget of £1,000 over three years for conference attendance;
- relevant tuition/bench fees for UK students.
Parkinson’s UK PhD studentship Closing date: 07 June 2013
Parkinson’s UK invites applications for its PhD studentships. These are offered to outstanding students undertaking research into Parkinson’s. Funding is available over three years to students based at UK higher education institutions and provides:
- a stipend of £15,000 per year (or £16,000 per year if in London);
- full PhD tuition fees at the UK/EU rate;
- a contribution of up to £10,000 per year towards research costs
Medical Research Council Industrial CASE studentships Closing Date: 26th July 2013 (FORECAST)
CASE studentships aim to provide PhD students with a challenging training experience within the context of a mutually beneficial collaboration between academic and non-academic partner organisations. Industrial CASE studentships are based at the academic institution, but must spend part of their time with the non-academic partner. This period must be a minimum of three months.
Funding for MRC studentships is provided to research organisations, such as universities, who select outstanding candidates for projects with leading researchers.
We do not fund students directly, so prospective students should contact the institution at which they wish to study.
Applications must demonstrate a relevance to MRC’s health mission
Sleeping pills owe half their benefits to placebo effect, study finds
Half of the benefit of taking sleeping pills comes from the placebo effect, according to a major new study published in the British Medical Journal.
Researchers re-analysed results from more than a dozen clinical trials of the most common type of sleeping tablets, known as Z-drugs (non-benzodiazepine hypnotics).
These drugs are frequently used in the UK and USA as a short-term treatment for insomnia with almost £25m worth of prescriptions handed out in Britain each year. However, some health experts have questioned whether the benefits of Z-drugs justify their side effects, which can include memory loss, fatigue and impaired balance.
Questions have also been raised about the validity of published research into the effects of these drugs based on trials sponsored by pharmaceutical companies themselves.
Academics from the University of Lincoln, Harvard Medical School and University of Connecticut conducted a meta-analysis of data from clinical trials of Z-drugs comparing drug effects with placebo effects. This type of comparison enables researchers to determine how much of the drug effect comes from the constituents of the drug itself, and how much is due to other factors (like the placebo response or regression to the mean).
They used data submitted by pharmaceutical companies to the US Food and Drug Administration (FDA) for approval of new products. This included 13 clinical trials containing 65 different comparisons and more than 4,300 participants.
The FDA collates results from both published and unpublished studies, enabling researchers to avoid common types of bias (such as reporting bias) which can undermine other research based on sponsored trials.
Their findings, published in this week’s British Medical Journal (17th December 2012), indicate that once the placebo effect is discounted, the drug effect is of ‘questionable clinical importance’.
Lead author Professor Niroshan Siriwardena, from the School of Health and Social Care at the University of Lincoln, said: “Our analysis showed that Z-drugs did reduce the length of time it took for subjects to fall asleep, both subjectively and as measured in a sleep lab, but around half of the effect of the drug was a placebo response.
“There was not enough evidence from the trials to show other benefits that might be important to people with sleep problems, such as sleep quality or daytime functioning.
“We know from other studies that around a fifth of people experience side effects from sleeping tablets and one in one hundred older people will have a fall, fracture or road traffic accident after using them.
“Psychological treatments for insomnia can work as effectively as sleeping tablets in the short-term and better in the long-term, so we should pay more attention to increasing access to these treatments for patients who might benefit.”
He said future studies of sleeping tablets should investigate a broader range of outcomes, not just time taken to fall asleep, and that pharmaceutical companies should be more transparent in disclosing results from their studies so that researchers can independently analyse their results.
The paper ‘Effectiveness of non-benzodiazepine hypnotics in the treatment of adult insomnia: meta-analysis of data submitted to the Food and Drug Administration’ was published in the British Medical Journal on 17th December 2012.
–Story Credits–
Ian Richards - PR Officer
E-mail: irichards@lincoln.ac.uk
Telephone: 01522 886042